ABSTRACT A total of five terpenes was isolated from the bark resin of Schinus molle L., Anacardiaceae, and their structures were determined by spectroscopic techniques. Among these compounds the sesquiterpene hydrocarbon terebinthene showed significant growth inhibitory activity against human colon carcinoma HCT-116 cells. Furthermore, terebinthene and pinicolic acid (5) also showed antibacterial activity against Staphylococcus aureus ATCC 25923 and Bacillus subtilis ATCC 6633.

ABSTRACT In the presented research we isolated and characterized compounds from Loricaria ferruginea (Ruiz & Pav.) Wedd., Asteraceae. To the best of our knowledge no data on any compounds from L. ferruginea have been published to this day. As main compounds of the hexane extract we found four known coumarins: 5,7-dimethoxycoumarin; 5,7,8-trimethoxycoumarin; 5-hydroxyobliquine and 5-methoxyobliquine. All the structures were determined by spectroscopic and spectrometric methods.

Abstract A phytochemical investigation of methanol and n-hexane extracts of tuber/roots of Corynaea crassa Hook. f., Balanophoraceae, led to the isolation and characterization of β-sitosterol, lupenone, β-amyrone, lupeol, and β-amyrine. Unusual complex 1:1 mixtures of lupenone/β-amyrone and lupeol/β-amyrine obtained from the extracts were identified by NMR and HR-MS experiments. The structure of the 1:1 lupenone/β-amyrone mixture was confirmed by X-ray analysis. These triterpene ketone derivatives, only distinguished either by 5- or 6-membered E ring, co-crystallize in one common unit cell in the solid state.

Palladium (II) and platinum (II) complexes 5 and 6 were synthesized using 1,2-dihydro-2,5-diphenyl-3H-1,2,4-triazole-3-thion 3 as a ligand from an isomeric mixture of 3 and 4. The unexpected structures of 5 and 6 were investigated by mass spectra, IR (DRIFT), and ESCA measurements as well as crystal structure determinations. The palladium (II) complex is tetranuclear with two groups of Pd central atoms with different coordination geometries. Two Pd atoms have coordination number 5 (square pyramidal) with a weak Pd-Pd bond between both coordination centers. The other Pd atoms show coordination number 4 (square planar). In the structure of the platinum (II) complex anion the Pt atom is surrounded by four sulphur atoms of the thion groups arranged in a square planar coordination. The crystal structure shows an extended system of hydrogen bonds that obviously determine the configuration of the complex anion.

Los complejos de paladio (II) 5 Y platino (II) 6 fueron sintetizados utilizando como ligando el 1,2-dihidro-2,5-difenil-3H-1,2,4-triazol-3-tiona 3 a partir de una mezcla de los isómeros 3 y 4. Las inesperadas estructuras de 5 y 6 fueron investigadas por el espectro de masas, IR (DRIFT) Y por mediciones ESCA; así como por determinación de las estructuras cristalinas. El complejo de paladio (II) es tetranuclear, con dos grupos de átomos centrales de paladio de diferente geometría de coordinación. Dos átomos de paladio tienen coordinación 5 (pirámide cuadrada) con un enlace débil Pd-Pd entre ambos centros de coordinación. Los otros átomos de paladio presentan número de coordinación 4 (cuadrada plana). En la estructura del anión complejo de platino (II), el átomo de Pt está rodeado por cuatro átomos de azufre del grupo tiona, en un arreglo de coordinación cuadrada plana. La estructura cristalina presenta un sistema amplio de enlaces de hidrógeno que obviamente determinan la configuración del anión complejo.

Compounds with substructures like CF 3 -C=C-NH-R are remarkable reactive towards primary amines. They behave like "ortho-fluorides" and are readily susceptible to elimination / addition sequences which can be linked together and performed as domino reactions.

Reacciones dominó con 5-azido- y 5-amino-4-trifluorometil-1,3 azoles. Los compuestos con sus sub-estructuras como CF 3 -C=C-NH-R, son considerablemente reactivos frente a aminas primarias. Ellos se comportan "ortho-fluoruros" y son fácilmente susceptibles respecto a la eliminación / adición de restos. Éstos pueden ser enlazados uno con otro dando así reacciones tipo dominó.