O objetivo deste trabalho foi avaliar as variáveis meteorológicas, a deficiência hídrica, o crescimento e a produtividade agroindustrial das variedades de cana-de-açúcar: RB72454, RB863129, RB867515, RB92579, RB93509, RB931003, RB951541 e RB971755, em cultivo de sequeiro, em duas safras, na região de Rio Largo - AL. As variáveis meteorológicas foram obtidas em uma estação automática, e o balanço hídrico foi feito pelo método de Thornthwaite & Mather. No período da pesquisa, a temperatura do ar variou de 16,6 a 35,9º C. No primeiro ciclo de produção, choveu 1.806 mm, e a cultura evapotranspirou 1.775 mm, e, no segundo ciclo, a precipitação pluvial somou 1.632 mm, e a evapotranspiração da cultura foi 1.290 mm. O excesso hídrico médio dos dois ciclos de produção foi 689 mm; e o déficit hídrico, 665 mm. Ou seja, mesmo resultando em uma precipitação pluvial superior à evapotranspiração da cultura, devido à má distribuição das chuvas, houve deficiência hídrica. A temperatura do ar não foi limitante para o crescimento da cana-de-açúcar. A produtividade agrícola média da cana-planta foi 86,8 t ha-1, em cana-soca foi 75,2 t ha-1, e o rendimento agroindustrial médio foi 12,9 e 10,9 toneladas de açúcar por hectare em cana-planta e cana-soca, respectivamente. As variedades mais produtivas foram a RB93509, a RB92579 e a RB863129.

The objective of this study was to evaluate the meteorological variables, water deficiency, growth, and agro-industrial yield of sugarcane varieties: RB72454, RB863129, RB867515, RB92579, RB93509, RB931003, RB951541, and RB971755, in rainfed crop in two harvests in the Rio Largo-AL region. The meteorological variables were obtained in an automatic station and water balance was done by Thornthwaite & Mather method. During the study period, the air temperature ranged from 16.6 to 35.9 ºC. In the first production cycle rained 1,806 mm and the crop evapotranspiration was 1,775 mm. In the second cycle, the rainfall totaled 1,632 mm and the crop evapotranspiration was 1,290 mm. The average water excess of two production cycles was 689 mm and the water deficit totaled 665 mm. The average agricultural productivity in the plant was 86.8 t ha-1, in the first ratoon was 75.2 t ha-1 and the agro-industrial yield average was 12.9 and 10.9 tons of sugar per hectare in the plant and first ratoon, respectively. The air temperature was not limiting to the growth of sugarcane and the rainfall was higher than the crop evapotranspiration, but due to poor distribution of the rains there was water deficit. The most productive varieties were RB93509, RB92579, and RB863129.

It has been demonstrated that carbon nanotubes (CNTs) associated with sodium hyaluronate (HY-CNTs) accelerate bone repair in the tooth sockets of rats. Before clinical application of HY-CNTs, it is important to assess their biocompatibility. Moreover, cardiac toxicity may be caused by the translocation of these particles to the blood stream. The aim of this study was to evaluate possible changes in cardiovascular function in male Wistar rats whose tooth sockets were treated with either CNTs or HY-CNTs (100 μg/mL, 0.1 mL). Blood pressure and heart rate were monitored in conscious rats 7 days after treatment. Cardiac function was evaluated using the Langendorff perfusion technique. The data showed no changes in blood pressure or heart rate in rats treated with either CNTs or HY-CNTs, and no significant changes in cardiac function were found in any of the groups. To confirm these findings, experiments were conducted in rats injected intraperitoneally with a high concentration of either CNTs or HY-CNTs (0.75 mg/kg). The same parameters were analyzed and similar results were observed. The results obtained 7 days following injection indicate that the administration of low concentrations of CNTs or HY-CNTs directly into tooth sockets did not cause any significant change in cardiovascular function in the rats. The present findings support the possibility of using these biocomposites in humans.

OBJETIVOS: Investigar a possibilidade da predição da acidemia no nascimento mediante dopplervelocimetria do ducto venoso e definir qual o melhor parâmetro e seus pontos de corte nessa predição em gestações com insuficiência placentária. MÉTODOS: Trata-se de estudo transversal e prospectivo que analisou 47 gestações únicas com insuficiência placentária e idade gestacional superior a 26 semanas, realizado no Hospital São Paulo (UNIFESP) e na Maternidade-Escola Assis Chateaubriand (UFC). A insuficiência placentária foi diagnosticada quando o índice de pulsatilidade da artéria umbilical encontrava-se acima do percentil 95 para a idade gestacional estimada. Fetos com anomalias estruturais ou cromossômicas foram excluídos. O doppler foi realizado a menos de 24 horas do parto. A amostra de sangue da artéria umbilical foi coletada imediatamente após o nascimento para análise da gasometria. Diagnosticou-se acidemia quando o pH encontrava-se abaixo de 7,20 na ausência de trabalho de parto e abaixo de 7,15 quando parto vaginal. Foram consideradas patológicas as acidemias metabólicas ou mistas. Construiu-se curva ROC para as velocidades S, D e A e para o IPV e as relações S/A e (S-A)/S do DV (variáveis independentes) e acidemia (variável dependente). O teste de MacNemar foi utilizado para comparar os parâmetros entre si. RESULTADOS: As velocidades absolutas S, D e A mostraram ser pobres preditoras da acidemia no nascimento. O IPV mostrou ser bom preditor de acidemia (área sob a curva ROC 0,79, p=0,003). As relações S/A e (S-A)/S também mostraram ser boas preditoras da acidemia (área sob a curva ROC 0,818, p=0,001). Os pontos de corte calculados foram: IPV = 0,76, S/A = 2,67 e (S-A)/S = 0,63. CONCLUSÕES: Os índices ângulo-independentes do doppler do DV mostraram excelente correlação com acidemia no nascimento nesta população. Não houve diferença estatisticamene significativa entre estes parâmetros.

OBJETIVES: To investigate the possibility of predicting acidemia at birth in pregnancies with placental insufficiency by Doppler velocimetry of the ductus venosus and to establish the best parameter and cut-off points in this prediction. METHODS: This was a prospective cross-sectional study, involving 47 single pregnancies with placental insufficiency after 26 weeks of gestation, carried out at the "Hospital São Paulo (UNIFESP) and Maternidade-Escola Assis Chateaubriand (UFC)". Placental insufficiency was defined as the umbilical artery pulsatility index above the 95th percentile for gestational age. Fetuses with chromosomal or structural anomalies were excluded. The time interval between the Doppler velocimetry and the birth was of less than 24 hours. The umbilical arterial blood samples were collected immediately after birth. Acidemia was defined as umbilical arterial pH < 7.2 in the absence of uterine contractions and < 7.15 in the presence of contractions. Metabolic or mixed acidemia at birth was considered pathological. Receiver operating characteristics (ROC) curves were calculated for S, D and A-velocities, pulsatility index for veins and the S/A ratio and (S-A)/S ratio of the ductus venosus. Parameters were compared using the MacNemar Test RESULTS: S, D and A-velocities of the ductus venosus were poor predictors of acidemia at birth. The pulsatility index for veins (area under the curve 0.79, p=0.003), S/A ratio and (S-A)/S ratio (area under the curve 0.818, p=0.001) of the DV were strongly related to fetal acidemia. The cut-off points calculated were: pulsatility index for veins = 0.76; S/A ratio = 2.67 and (S-A)/S ratio = 0.63. CONCLUSIONS: The angle-independent indices of the DV Doppler are adequate for the diagnosis of fetal acidemia in gestations with placental insufficiency. No statistically significant differences were observed between these parameters.

RESUMO Dentre as complicações associadas à anestesia retrobulbar e peribulbar, perfuração do globo ocular parece ser das mais importantes. Recente estudo ultrassonográfico demonstrou que, em pacientes submetidos à anestesia retrobulbar para cirurgia de catarata com comprimento axial normal, a ponta da agulha usada para injeção retrobulbar se encontrava muito próxima do globo ocular, as vezes até indentando sua parede. Tal fato pode se tornar extremamente perigoso em olhos com comprimento axial aumentado, como nos altos míopes. Demonstramos a eficácia e segurança do uso da técnica de anestesia retrobulbar com catéter flexível de Teflon em 15 pacientes com comprimento axial ocular ântero-posterior aumentado e candidatos à facectomia.

SUMMARY Globe perforation is one of the most serious complications associated with retrobulbar or peribulbar anesthesia, with high impact on future vision. Ultrassonography of retrobulbar space in patients submitted to retrobulbar anesthesia with normal ocular axial length has shown that retrobulbar needle tips are closer to the globe than previously thought. This could be dangerous in patients with enlarged eye such as in high myopia. We describe the use of retrobulbar anesthesia with a flexible catheter in 15 patients with extended axial ocular length.