Resumo: O objetivo do artigo é discutir como o Estado brasileiro tem buscado regulamentar práticas religiosas em comunidades terapêuticas (CTs) e como elas reagem a esse movimento. Para isso, analisamos as normativas nacionais que regulamentam as CTs no Brasil e realizamos estudo de caso sobre o estado de São Paulo. A metodologia baseia-se na triangulação de técnicas: revisão bibliográfica, análise documental e entrevistas. Nosso principal argumento é que a categoria espiritualidade é coconstruída a partir de interações e conflitos, se tratando de um encaixe institucional que, ao mesmo tempo em que permite a manutenção da religião como um dos tripés do tratamento proposto pelas CTs, também assegura a elas um caráter de pluralidade religiosa, abrindo espaço para o financiamento estatal. Resumo (CTs movimento isso Paulo baseiase baseia técnicas bibliográfica entrevistas conflitos religiosa estatal

Abstract: The article aims to analyze how the Brazilian state has sought to regulate religious practices in therapeutic communities (TCs) and how these organizations react to this process. For this, we analyzed the national regulations of TCs in Brazil and carried out a case study on the state of São Paulo. The methodology consists of a bibliographic review, document analysis, and interviews. Our main argument is that the spirituality category is co-constructed through interactions and conflicts, being an institutional fit that, while allowing the maintenance of religion as one of the tripods of the treatment proposed by TCs, also ensures them a character of religious plurality, opening space for state funding. Abstract (TCs process Paulo review analysis interviews coconstructed co constructed conflicts plurality funding

Substances that inhibit the growth of Mycobacterium tuberculosis could potentially be used as antibiotics. These substances could also be added to test culture media to improve the speed of tuberculosis diagnosis. The aim of this work was to investigate the influence of culture filtrates of endophytic fungi isolated from P. aduncum L. on the growth of M. tuberculosis. To achieve this objective, the following methodology was used: a) endophytic fungi were isolated from the leaves and stems of P. aduncum L.; b) the isolated fungi were submitted to submerged bioprocessing; c) culture filtrates from the bioprocess were assayed to evaluate their effect on the growth of M. tuberculosis. We isolated 315 fungal types, which represented 85 morphologies, from different parts of P. aduncum L. The bioassays were performed on 82 culture filtrates and 6 plant extracts and resulted in the detection of 1 culture filtrate that stimulated the growth of M. tuberculosis and 15 that inhibited microbial growth. None of the phytochemical extracts had an effect on the growth of M. tuberculosis. In conclusion, we observed that the endophytic fungi isolated from P. aduncum L. (Piperaceae) produced extracellular metabolites (present in the culture filtrate) that affect the growth of M. tuberculosis. These compounds have the potential to be used as antimicrobials or in the diagnosis of tuberculosis.