ABSTRACT Neea is one of the largest genera of Nyctaginaceae and comprises approximately 80 species distributed in the Neotropical region. Here, we report for the first time the occurrence of Neea madeirana in Peru, almost 50 years after it was first collected in this country, but was misidentified as Guapira noxia. We also insert N. madeirana in the identification key for Peruvian species of Neea and update the distribution map of N. madeirana. Given that we have not located any posterior specimen of G. noxia in Peruvian collections, and the original specimens cited as G. noxia correspond to N. madeirana, we suggest the exclusion of G. noxia from the Peruvian flora checklist.

RESUMO Neea é um dos maiores gêneros de Nyctaginaceae e compreende aproximadamente 80 espécies distribuídas na região neotropical. Aqui, relatamos, pela primeira vez, a ocorrência de Neea madeirana no Peru, quase 50 anos depois de ter sido coletada pela primeira vez neste país, mas foi erroneamente identificada como Guapira noxia. Também inserimos N. madeirana na chave de identificação para espécies peruanas de Neea e atualizamos o mapa de distribuição de N. madeirana. Dado que não localizamos nenhum espécime posterior de G. noxia nas coleções peruanas, e os espécimes originais citados como G. noxia correspondem a N. madeirana, sugerimos a exclusão de G. noxia da flora peruana.

Objectives: To summarize evidence-based cognitive-behavioral therapy (CBT) treatment and propose clinical interventions for adult patients with obsessive-compulsive disorder (OCD). Methods: The literature on CBT interventions for adult OCD, including BT and exposure and response prevention, was systematically reviewed to develop updated clinical guidelines for clinicians, providing comprehensive details about the necessary procedures for the CBT protocol. We searched the literature from 2013-2020 in five databases (PubMed, Cochrane, Embase, PsycINFO, and Lilacs) regarding study design, primary outcome measures, publication type, and language. Selected articles were assessed for quality with validated tools. Treatment recommendations were classified according to levels of evidence developed by the American College of Cardiology and the American Heart Association. Results: We examined 44 new studies used to update the 2013 American Psychiatric Association guidelines. High-quality evidence supports CBT with exposure and response prevention techniques as a first-line treatment for OCD. Protocols for Internet-delivered CBT have also proven efficacious for adults with OCD. Conclusion: High-quality scientific evidence supports the use of CBT with exposure and response prevention to treat adults with OCD.

Objectives: To summarize evidence-based pharmacological treatments and provide guidance on clinical interventions for adult patients with obsessive-compulsive disorder (OCD). Methods: The American Psychiatric Association (APA) guidelines for the treatment of OCD (2013) were updated with a systematic review assessing the efficacy of pharmacological treatments for adult OCD, comprising monotherapy with selective serotonin reuptake inhibitors (SSRIs), clomipramine, serotonin and norepinephrine reuptake inhibitors (SNRIs), and augmentation strategies with clomipramine, antipsychotics, and glutamate-modulating agents. We searched for the literature published from 2013-2020 in five databases, considering the design of the study, primary outcome measures, types of publication, and language. Selected articles had their quality assessed with validated tools. Treatment recommendations were classified according to levels of evidence developed by the American College of Cardiology and the American Heart Association (ACC/AHA). Results: We examined 57 new studies to update the 2013 APA guidelines. High-quality evidence supports SSRIs for first-line pharmacological treatment of OCD. Moreover, augmentation of SSRIs with antipsychotics (risperidone, aripiprazole) is the most evidence-based pharmacological intervention for SSRI-resistant OCD. Conclusion: SSRIs, in the highest recommended or tolerable doses for 8-12 weeks, remain the first-line treatment for adult OCD. Optimal augmentation strategies for SSRI-resistant OCD include low doses of risperidone or aripiprazole. Pharmacological treatments considered ineffective or potentially harmful, such as monotherapy with antipsychotics or augmentation with ketamine, lamotrigine, or N-acetylcysteine, have also been detailed.

RESUMO O Plano Educacional Individualizado é importante na inclusão de estudantes com Transtorno do Espectro Autista por conduzir a prática pedagógica dos professores em direção às necessidades educacionais desses alunos, com base em um trabalho colaborativo com os pais e equipe multiprofissional. Este estudo buscou descrever, por meio de um estudo de caso, a implementação do Plano Educacional Individualizado na fase de elaboração e verificar sua influência sobre o trabalho colaborativo da equipe docente em uma escola de ensino fundamental. A equipe escolar respondeu a um questionário sobre trabalho colaborativo antes e depois de quatro meses da elaboração do Plano Educacional Individualizado para um estudante com autismo. Os resultados mostraram melhora em cada dimensão do trabalho colaborativo da equipe escolar. O potencial do Plano Educacional Individualizado para o maior envolvimento dos professores em torno de objetivos comuns para a aprendizagem de alunos com Transtorno do Espectro Autista por meio do trabalho colaborativo é discutido. multiprofissional descrever caso fundamental autismo discutido

RESUMEN El Plan Educativo Individualizado es importante en la inclusión de alumnos con Trastorno del Espectro Autista ya que orienta la práctica pedagógica de los docentes hacia las necesidades educativas de estos alumnos, a partir del trabajo colaborativo con los padres y un equipo multidisciplinario. Este estudio buscó describir, a partir de un estudio de caso, la implementación del Plan Educativo Individualizado en la fase de elaboración y verificar su influencia en el trabajo colaborativo del profesorado de una escuela primaria. El equipo de la escuela respondió un cuestionario sobre trabajo colaborativo antes y después de cuatro meses de la elaboración del Plan Educativo Individualizado para un estudiante con autismo. Los resultados mostraron una mejora en cada dimensión del trabajo colaborativo del equipo escolar. Se discute el potencial del Plan Educativo Individualizado para una mayor participación docente en torno a objetivos comunes para el aprendizaje de los estudiantes con Trastorno del Espectro Autista a través del trabajo colaborativo. multidisciplinario describir caso primaria autismo escolar

ABSTRACT The Individualized Educational Plan is important in the inclusion of students with Autism Spectrum Disorder because it leads the pedagogical practice of teachers towards the educational needs of these students, from collaborative work with parents and a multidisciplinary team. This study sought to describe, from a case study, the implementation of the Individualized Educational Plan in the elaboration phase and verify its influence on the collaborative work of the school team in an elementary school. The school team answered a questionnaire about collaborative work before and after four months of the Individualized Educational Plan elaboration for a student with autism. The results showed improvement in each dimension of the school team's collaborative work. The potential of Individualized Educational Plan for greater teacher involvement around common goals for the learning of students with Autism Spectrum Disorder through collaborative work are discussed. describe autism teams s discussed

RESUMO Este estudo teve como objetivo verificar o impacto de programas comerciais de resfriamento rápido na qualidade físico-química de mangas ‘Rosa’. O estudo foi realizado em um packing house de mangas na região do Vale do São Francisco, Petrolina, PE, Brasil, entre Agosto e Outubro de 2018. O experimento seguiu um delineamento em blocos casualizados com três repetições e um palete por repetição. Os tratamentos foram organizados em esquema fatorial 2 × 2 × 3 (dois tempos de resfriamento rápido [120 e 240 min] × dois tempos de armazenamento x três posições no palete). Sessenta mangas foram distribuídas proporcionalmente em três camadas de diferentes alturas em cada um dos seis paletes. Três paletes foram submetidos ao resfriamento rápido por 120 min e outros três por 240 min. Todas as frutas foram armazenadas por 7 e 14 dias a 6 °C mais três dias de vida de prateleira a 20 °C. Independentemente do programa de resfriamento e da posição da fruta no palete, o tempo de resfriamento de sete oitavos (SECT) não foi alcançado. A acidez titulável do fruto com 240 min de resfriamento rápido diminuiu significativamente após 14 dias de armazenamento refrigerado. A perda de peso das frutas, a firmeza da polpa, a matéria seca e o teor de sólidos solúveis não foram afetados pelos programas de resfriamento rápido, tanto após o armazenamento quanto durante a vida de prateleira. O programa comercial de resfriamento rápido pode ser executado por 120 min.

ABSTRACT This study aimed to verify the impact of commercial fast-cooling programs on physicochemical quality of ‘Rosa’ mangoes. The study was carried out in a mango packing house in the São Francisco Valley region, Petrolina, PE, Brazil, between August and October 2018. The experiment followed a randomized block design, with three replicates and one pallet per replicate. The treatments were organized in a factorial scheme 2 × 2 × 3 (two fast-cooling times [120 and 240 min] × two storage times x three positions in the pallet). Sixty mangoes were proportionally distributed in three layers at different heights on each of the six pallets. Three pallets were subjected to fast cooling for 120 min and the other three for 240 min. All fruits were stored for 7 and 14 days at 6 °C plus three days of shelf-life at 20 °C. Regardless of cooling program and fruit position in the pallet, the seven-eighths cooling time (SECT) was not attained. The titratable acidity of fruits under 240-min fast cooling decreased significantly after 14 days of cold storage. Fruit weight loss, pulp firmness, dry matter, and soluble solids content were not affected by the fast-cooling programs, both after storage and during shelf-life period. Commercial fast-cooling program can be performed for 120 min.

Abstract Brazil internalized UNCINTRAL’s Model Law through bill 14.112/2020, act that aims, among others, cooperation between the courts that deal with the insolvence of a cross-board company. However, it was also internalized the exception of public policy, mechanism that allows a brazilian judge deny recognition of a foreign insolvence suit that is manifestly contrary to the public policy. This paper is framed from a finding that the approval of that bill is an international commitment adopted by the country and that the exception of public policy is a compromise of the country with its own civilization standards. From this premise, our propose is, with an empiral methodology, construct examples of manifestly contrary to the public policy. The aim desired, therefore, is establish theorical models of an appropriate application of the public policy exception.

Resumo O Brasil internalizou a Lei Modelo da UNCINTRAL através da Lei n. 14.112/2020, lei que tem por objetivo, dentre outros, a cooperação internacional entre jurisdições que tratem da insolvência de uma mesma empresa transnacional. Porém, também foi internalizada a partir da Lei Modelo a chamada cláusula de barreira da ordem pública, exceção que permite que o juiz negue eficácia ao processo de insolvência estrangeiro que represente manifesta ofensa à ordem pública do Brasil. O presente artigo se estrutura a partir da constatação que a aprovação da lei é um compromisso internacional assumido pelo país e que a cláusula de barreira da ordem pública é um compromisso do país com seu próprio padrão civilizatório. Tomada tal premissa, propõe-se, com metodologia empírica hipotética, construir exemplos de manifesta ofensa à ordem pública. O escopo pretendido, portanto, é definir modelos teóricos para aplicação adequada da cláusula de barreira.

Obsessive-compulsive disorder (OCD) is a common psychiatric condition classically characterized by obsessions (recurrent, intrusive and unwanted thoughts) and compulsions (excessive, repetitive and ritualistic behaviors or mental acts). OCD is heterogeneous in its clinical presentation and not all patients respond to first-line treatments. Several neurocircuit models of OCD have been proposed with the aim of providing a better understanding of the neural and cognitive mechanisms involved in the disorder. These models use advances in neuroscience and findings from neuropsychological and neuroimaging studies to suggest links between clinical profiles that reflect the symptoms and experiences of patients and dysfunctions in specific neurocircuits. Several models propose that treatments for OCD could be improved if directed to specific neurocircuit dysfunctions, thereby restoring efficient neurocognitive function and ameliorating the symptomatology of each associated clinical profile. Yet, there are several important limitations to neurocircuit models of OCD. The purpose of the current review is to highlight some of these limitations, including issues related to the complexity of brain and cognitive function, the clinical presentation and course of OCD, etiological factors, and treatment methods proposed by the models. We also provide suggestions for future research to advance neurocircuit models of OCD and facilitate translation to clinical application.

Abstract A novel pigment of β-LiAlSi2O6:Cr ceramic was developed by a partial proteic sol-gel process, using gelatin as a ligand. X-ray diffraction (XRD), energy dispersive spectroscopy (EDS) and visible and near-infrared diffuse reflectance spectroscopy (vis-NIR DRS) were performed. XRD results confirmed that the crystal structure of the lattice corresponded to β-LiAlSi2O6 (or β‑spodumene), and the addition Cr3+ ions by doping did not interfere in the formation of this crystalline phase. EDS confirmed the homogeneous existence of Cr3+ dopant in β‑LiAlSi2O6 particles. From the vis‑NIR DRS, selective absorption of visible light wavelengths was identified in the bands of 425 nm and 600 nm, resulting in the perception of a yellowish-green color when β-LiAlSi2O6 is doped with Cr3+. CIE-XYZ colorimetric coordinates were generated to characterize the resulting colors. The obtained results demonstrated the viability of β‑LiAlSi2O6:Cr synthesis by a proteic sol‑gel route and its great potential for obtaining a yellowish-green ceramic pigment.

ABSTRACT This paper aimed to develop predictive models to determine total soluble solids, firmness, and ripening stages of ‘Pacovan’ bananas, using Vis-NIR spectroscopy and machine learning algorithms. A total of 384 bananas were divided into different days of storage (0, 3, 6, 9, 12, 15, 18, and 21 days) at two temperatures (25°C and 20°C). Bananas were subjected to spectral analysis using a spectrometer operating in spectral range of 350 – 2500 nm. Physicochemical parameters of quality, total soluble solids, and firmness were determined by reference analyses. Different machine learning algorithms were used to develop regression models and supervised classification. The best model for total soluble solids was the Random Forest with variable selection, showing an R2cv of 0.90 and RMSECV of 2.31. The best model for firmness was the Support Vector Machine with variable selection, showing an R2cv of 0.84 and RMSECV of 7.98. The best classification model for different ripening stages was the Multilayer Perceptron with variable selection, which achieved the precision of 74.22%. Therefore, Vis-NIR spectroscopy associated with machine learning algorithms is a promising tool for monitoring the quality and ripening stages of ‘Pacovan’ bananas.

Abstract Mango quality is affected by thermal storage conditions. Therefore, it is important to use cooling techniques and their monitoring to maintain desirable properties in the fruit. The objective of this study was to evaluate the effects of commercial rapid cooling programs on the quality of ‘Rosa’ mango. Mangoes were distributed on different horizontal positions of six pallets. All pallets were put through two rapid cooling times, three pallets for 120 minutes and three pallets for 240 minutes. Subsequently, the fruits were stored in a cold chamber for 7 and 14 days, followed by an evaluation of shelf life for 3 days at 20°C. Experimental design was in randomized blocks with three replicates, with one pallet per replicate. The weight, pH, and skin color of the fruit were assessed. According to the results, fruits closer to the air inlet in the packages showed the highest cooling rates. After storage and shelf life, quality parameters were not significantly affected by the rapid cooling programs. In conclusion, the 120-minute program can be satisfactorily adopted for the rapid cooling process of the ‘Rosa’ mango, considering the reduction of energy costs and the reduction of the dwell time of the fruit in the cold chamber.

RESUMO A fim de minimizar o impacto ambiental ocasionado pelas misturas asfálticas a quente surgiram as chamadas misturas asfálticas mornas. Este trabalho investigou o uso da cera de carnaúba tipo 1, nos teores de 1, 2 e 3% por peso de ligante asfáltico classificado com penetração 50/70, como aditivo incorporado às misturas asfálticas para a obtenção de misturas mornas. Os resultados apontaram uma redução de até 9 °C na temperatura de mistura e 7 °C na temperatura de compactação com o uso de 2 e 3% de cera. As misturas asfálticas foram dosadas pelo método Superpave e submetidas a ensaios mecânicos: ensaios de resistência à tração, dano por umidade induzida, módulo de resiliência, módulo dinâmico e vida de fadiga. A incorporação de 2% acarretou resultados superiores quanto ao desempenho mecânico das misturas asfálticas, principalmente ao dano por umidade induzida, e uma maior redução das temperaturas de mistura e compactação. Portanto, as misturas cumpriram as exigências mecânicas e se apresentaram viáveis tecnicamente, podendo contribuir para mitigação de danos ambientais como a redução do consumo de energia e as emissões de CO2 em usinas asfálticas.

ABSTRACT In order to minimize the environmental impact caused by hot asphalt mixtures, the so-called warm asphalt mixtures emerged. This work investigated the use of type 1 carnauba wax, at levels of 1, 2, and 3% by weight of asphalt binder classified with penetration 50/70, as an additive incorporated into asphalt mixtures to obtain warm mixtures. The results showed a reduction of up to 9 °C in the mixing temperature and 7 °C in the compaction temperature with the use of 2 and 3% wax. The asphalt mixtures were dosed by the Superpave method and submitted to mechanical tests: tensile strength tests, induced moisture damage, modulus of resilience, dynamic modulus and fatigue life. The incorporation of 2% resulted in superior results in terms of the mechanical performance of the asphalt mixtures, mainly in terms of induced moisture damage, and a more significant reduction in mixing and compaction temperatures. Therefore, the mixtures complied with the mechanical requirements and were technically viable, contributing to the mitigation of environmental damages such as the reduction of energy consumption and CO2 emissions in asphalt plants.

Abstract Aiming to test the capacity of retention of carotenoids in tissues, Lophiosilurus alexandri juveniles were fed diets containing 0, 25, 50, 100, 200, and 400 mg/kg of synthetic astaxanthin for 62 days. The inclusion of astaxanthin did not result in significant differences in growth, weight gain, apparent feed conversion, and feed efficiency of the fish. Blood biochemistry and liver histology did not change with the different treatments. At the level of 100 mg/kg of inclusion, there were the highest levels of carotenoids in the blood, and muscle and the smallest difference between the muscle x integument ratio.

ABSTRACT Objective: To develop and validate a comic book for the adult population about prevention and first aid for burns. Method: Applied quantitative research conducted at a university hospital, guided by the Social Cognitive Theory. A comic book was developed, followed by Content Validation with 12 experts and Semantic Validation with 30 adults. The Educational Content Validation Instrument in Health and Suitability Assessment of Materials were used for data collection and the analysis was carried out by Content Validity Index, with a minimum of 0.8. Results: The final version has ten pages, both printed and virtual form. The overall agreement rate was 0.963 in content and 0.987 in semantics. The main adjustments were in the language and layout of the cover. Conclusion: The levels of agreement were satisfactory, determining the validity of the Comic Book, configuring it as a simple and accessible resource for health education about burns for adults.

RESUMEN Objetivo: Desarrollar y validar un Comics para población adulta sobre prevención y primeros auxilios para quemaduras. Método: Investigación aplicada, cuantitativa, realizada en un hospital universitario, guiada por la Teoría Social Cognitiva. Se elaboró un Cómic, seguido de Validación de Contenido con 12 expertos y Validación Semántica con 30 adultos. Para la recolección de datos se utilizó el Instrumento de Validación de Contenido Educativo en Saludy Suitability Assessment of Materials y el análisis se realizó por Índice de Validación de Contenido, con un mínimo de 0,8. Resultados: La versión final tiene diez páginas, en forma impresa y virtual La tasa de acuerdo global fue de 0,963 en contenido y 0,987 en semántica. Los principales ajustes fueron en el lenguaje y el diseño de la portada. Conclusión: Los niveles de acuerdo fueron satisfactorios, determinando la validez de la Historieta, configurando la como un recurso sencillo y accesible para la educación en salud sobre quemaduras para adultos.

RESUMO Objetivo: Elaborar e validar uma História em Quadrinhos para a população adulta sobre prevenção e primeiros socorros para queimaduras. Método: Pesquisa aplicada, quantitativa, conduzida em hospital universitário, norteada pela Teoria Social Cognitiva. Elaborou-se uma História em Quadrinhos, seguida de Validação de Conteúdo com 12especialistas e Validação Semântica com 30 adultos. Utilizou-se o Instrumento de Validação de Conteúdo Educativo em Saúde e Suitability Assessment of Materials para coleta dos dados e a análise deu-se por Índice de Validação de Conteúdo, com mínimo de 0,8. Resultados: A versão final possui dez páginas, na modalidade impressa e virtual. O índice global de concordância foi 0,963 em conteúdo e 0,987 em semântica. As adequações principais foram na linguagem e layout da capa. Conclusão: Os níveis de concordância foram satisfatórios, determinando a validade da História em Quadrinhos, configurando-a como recurso simples e acessível para a educação em saúde sobre queimaduras para adultos.

Resumo Embora os tumores lipomatosos sejam comuns, a ocorrência intra-articular é extremamente rara e escassamente descrita na literatura. Em relação a essas entidades raras, a maioria é benigna, tumores de crescimento progressivo e geralmente ocorrem no joelho, mas é crucial distinguir o menos frequente lipoma arborescens (LA) do lipoma sinovial mais raro, pois diferem na apresentação e na patogênese. A ressonância magnética é o exame de escolha na avaliação e no diagnóstico diferencial desses casos, desempenhando um papel central nos dias de hoje. A excisão e sinovectomia, quer artroscópica quer por artrotomia, proporcionam bons resultados com baixas taxas de recorrência. Ao relatar dois casos distintos tratados cirurgicamente de tumores lipomatosos intra-articulares do joelho, os autores pretendem revisar a literatura e discutir sua etiologia, aspectos clínicos e de imagem, bem como a abordagem do tratamento.

Abstract Although lipomatous tumors are common, intra-articular occurrence is exceedingly rare and sparsely described in the literature. Regarding these rare entities, most are benign, progressively growing tumors and often occur in the knee, yet it is crucial to distinguish the less infrequent lipoma arborescens (LA) from the rarer synovial lipoma, as they differ in presentation and pathogenesis. Magnetic resonance imaging is the exam of choice in their assessment and in differential diagnosis, playing a central role nowadays. Excision and synovectomy, either arthroscopic or by arthrotomy, provide good outcomes with low recurrence rates. By reporting two surgically treated distinct cases of intra-articular lipomatous tumors of the knee, the authors intend to review the literature and discuss their etiology, clinical and imaging aspects as well as treatment approach.

ABSTRACT Chlorophyll content is a widely used parameter for nutritional status diagnosis in sugarcane. This study aimed to develop a predictive model of chlorophyll content in sugarcane seedlings using spectral imagery analysis within the electromagnetic spectrum visible range. The experiment was carried out in a split-plot design, with two fertilization rates and three sugarcane cultivars. For chlorophyll analysis, 144 leaves were collected from seedlings. Chlorophyll contents were extracted and measured by SPAD-502 meter. Spectral images within the range of 480 to 710 nm were analyzed using reflectance, absorbance (white source), and fluorescence (source at 405 and 470 nm) responses. Predictive models were developed using multivariate regression methods such as Principal Component Regression and Partial Least Squares Regression. We chose the best model through absorbance response using variable selection and the PLSR method (R2P = 0.718 and RMSEP = 7.665). The wavelengths of 480, 490, 500, 600, 630, and 640 nm were identified as the best for total chlorophyll content determination. The spectral image processing-based method can provide a chlorophyll measurement equivalent to SPAD, with the advantage of having a higher spatial coverage over the entire leaf area. Besides, it can also support automation of the chlorophyll measurement in greenhouses.