RESUMO: Os organismos aquáticos têm sido alvo de constante interesse por conta de suas características nutricionais e da crescente disponibilização na alimentação humana. Sendo assim, estudos relacionados a organismos nocivos presentes nos ecossistemas aquáticos têm se intensificado, como, por exemplo, acerca dos parasitos, que podem interessar à saúde pública como zoonose ou comprometer a higidez dos hospedeiros. Os peixes apresentam sua fauna parasitária característica em que o equilíbrio do estado saúde-doença é dependente da interação da tríade parasito-hospedeiro-ambiente. Com isso, o objetivo do presente trabalho foi fazer uma revisão bibliográfica de aspectos gerais e da epidemiologia dos parasitos de Hoplias aff. malabaricus Bloch, 1794, amplamente distribuído e consumido no Brasil.

ABSTRACT: Aquatic organisms are a subject of great interest because of their nutritional value and their high availability as human food. As a result, an increasing number of studies are being conducted on potentially harmful aquatic organisms such as aquatic parasites that compromise host health, as well as affect public health by zoonosis. A balance between the characteristics of healthy and diseased states in fish infected by parasitic fauna is dependent on parasite-host-environment interactions. Here, we have compiled a bibliographical review of the general aspects and epidemiology of the parasites of Hoplias aff. malabaricus Bloch, 1794, a widely distributed and consumed fish species in Brazil.

ABSTRACT This study assessed the protective effect of the carotenoid bixin and annatto seeds against possible nephrotoxicity induced with a single peritoneal administration of pharmacological cisplatin in male Wistar rats. After 48 h, the blood cell differential count showed a significant reduction in neutrophil counts in rats that received a diet rich in bixin when compared to the group that received only cisplatin. The use of cisplatin led to an increase in kidney weight. The carotenoid bixin attenuated renal injury, characterized by increased polymorphonuclear infiltration. No protective effect was observed with respect to Annatto. These results demonstrate the role of toxic cisplatin and suggest that bixin affords a protective effect against cisplatin-induced nephrotoxicity in adult Wistar rats.

O objetivo deste estudo longitudinal foi avaliar a efetividade de um programa de saúde bucal, iniciado durante a gestação, sobre a experiência de cárie de primigestas e seus filhos. Oitenta e uma gestantes, pertencentes a classes sociais pouco favorecidas, foram selecionadas com base no diagnóstico clínico de lesões de cárie ativas e foram divididas aleatoriamente em grupo controle ou experimental. A condição dentária inicial foi estabelecida através do índice CPOS e do diagnóstico das lesões de mancha branca. As medidas preventivas foram aplicadas durante a gestação e 6 e 12 meses após o parto. Ambos os grupos receberam abordagem educativa. O grupo experimental recebeu adicionalmente tratamento com anti-microbianos e adequação bucal utilizando cimento de ionômero de vidro. A prevalência de crianças cárie-ativas com a idade de dois anos foi de 33,3% no grupo controle e 14,7% no grupo experimental. Foi observada diferença significativa na prevalência de cárie entre crianças com e sem placa dentária visível. O número médio de superfícies com lesões de cárie (incluindo as desmineralizações) foi maior para as crianças do grupo controle quando comparadas às do grupo experimental (6,3 x 3,2), porém sem atingir significância estatística. O incremento de cárie na dentição da mãe apresentou correlação significativa com a incidência de cárie na dentição das crianças. Estes dados suportam a evidência de associação entre a incidência de cárie na primeira infância e a presença de placa, assim como a influência significativa de fatores maternos.

The aim of this prospective study was to determine the effectiveness of caries preventive measures started during pregnancy on the caries experience of first-time mothers and their infants. Eighty-one pregnant women with low social background were selected on the basis of the presence of active carious lesions and were randomly divided into control (38) and experimental (43) groups. The initial dental status (DMFS and white spot lesions) was established through clinical examination. The prophylactic measures were repeated during pregnancy and 6 and 12 months after delivery. Both groups received primary care intervention. They were instructed in relation to the etiologic factors of dental caries and received oral hygiene kits. Oral hygiene instructions were reinforced through interactive brushing. The experimental group also received antimicrobial treatment (topical application of NaF and iodine solution immediately after prophylaxis and 3 and 5 days later) and restorative care using glass ionomer cement. By the time the children were 2 years of age, 33.3% of the infants in the control group and 14.7% in the experimental group had caries activity. A significant difference in caries prevalence was observed between children with and without visible dental plaque. The mean number of tooth surfaces with carious lesions (including areas of demineralization) was higher among the children in the control group compared to the experimental group (6.3 x 3.2), however, with no statistical significance. Maternal caries increase was a significant factor influencing the caries experience of the children. These data support the evidence of an association between caries prevalence in young children and clinical (dental plaque) and maternal factors.