Patients with gastroesophageal reflux may have extra-esophageal manifestations. We report a 46 years old ex-smoker woman presenting with a sensation of burning mouth, xerostomia and glossitis. The patient had a history of heartburn, dysphonia and cough. Mouth examination showed a bad hygiene and abundant accumulation of plaque. Esophageal pH measurement was abnormal. Laryngoscopy showed a posterior laryngeal inflammation and mucous secretion. With these data, a diagnosis of gastroesophageal reflux was reached.

Los pacientes con reflujo gastroesofágico pueden tener manifestaciones extra esofágicas. Presentamos una mujer ex fumadora de 46 años que se presentó con sensación de quemazón en la boca, xerostomia y glositis. La paciente tenía además una historia de pirosis retroesternal, disfonía y tos. El examen bucal mostró una mala higiene bucal con abundante acumulación de sarro. Una medición de pH esofágico fue anormal. La laringoscopia mostró una inflamación laríngea posterior y secreción mucosa. Con estos antecedentes se llegó al diagnóstico de reflujo gastroesofágico.

OBJECTIVE: The aim of this systematic review was to assess the role of microsurgical reconstruction of the jaws in patients with bisphosphonate-related osteonecrosis, and biological complications after an observation period of at least 12 months. Material and methods: An electronic MEDLINE search supplemented by manual searching was conducted to identify studies reporting data of at least 12 months observation on the microsurgical reconstruction of the jaws in patients with bisphosphonate-related osteonecrosis. RESULTS: Four studies resulted eligible for the analysis yielded. Three out of five studies were free of complications, with a success rate of 100% as no recurrence of osteonecrosis was registered. CONCLUSIONS: Microsurgical reconstruction of the jaws represents a valid treatment modality in patients with bisphosphonate-related osteonecrosis at 3rd stage of the disease.