Resumo O vírus da hepatite C (HCV) é o grave problema de saúde pública das doenças hepáticas. Aproximadamente 170 milhões de pessoas no mundo estão infectadas com HCV; no Paquistão, a doença tem alto índice de ocorrência. O presente estudo prevê uma prevalência atualizada do HCV e distribuição genotípica na população geral do distrito de Mardan, Khyber Pakhtunkhwa (KP), Paquistão. As amostras de sangue de 6.538 indivíduos, incluindo 3.263 homens e 3.275 mulheres, foram analisadas para o antígeno de superfície da hepatite C por teste imunocromatográfico (ICT), ensaio imunoenzimático (ELISA) e reação em cadeia da polimerase de transcrição reversa (PCR). Verificou-se que 396 (12,13%) de 3.263 indivíduos continham anticorpos no sangue contra o HCV, enquanto entre as diferentes faixas etárias as maiores incidências de anticorpos anti-HCV foram encontradas na faixa etária de 31 a 40 anos (11,01%). As amostras positivas para ICT foram posteriormente rastreadas por nested PCR para determinar a existência de HCV-RNA ativo. Identificou-se que 7,11% (3.263) do total da população (6.538) testada foram positivos, dentre os quais 461 (14,07%) mulheres possuíam anticorpos no sangue contra o HCV. Nossos dados mostraram que a infecção total pelo HCV na população investigada foi de 5,78%. Maior porcentagem de prevalência de HCV foi detectada em homens do que em mulheres nas faixas etárias de 31-40 e 41-50. Para comparar a prevalência de genótipos de HCV com relação à idade no genótipo masculino e feminino 3a foi encontrado o genótipo mais prevalente seguido por 1a, 2a e 3b, respectivamente.

Abstract Hepatitis C virus (HCV) is the serious global public health burden of liver disease. Approximately 170 million people in the world are infected with (HCV). In Pakistan, where the disease has high occurrence rate. The present study envisages an up-to-date prevalence of HCV and genotypic distribution in the general population of Mardan District, Khyber Pakhtunkhwa (KP), Pakistan. The blood samples from 6,538 individuals including 3,263 males and 3,275 females were analyzed for hepatitis C surface antigen by Immuno-chromatographic test (ICT), Enzyme-linked immunosorbent assay (ELISA), and reverse transcription-polymerase chain reaction (PCR). It was found that 396 (12.13%) out of 3263 individuals contained antibodies in their blood against HCV, while among the different age groups, the highest incidences of HCV antibodies were found in the 31-40 age group (11.01%). The ICT positive samples were further screened by nested PCR to determine the existence of active HCV-RNA. It was identified that 7.11% (3263) of the total population (6538) tested was positive, among which the 461 (14.07%) females possessed antibodies in their blood against HCV. Our data showed total HCV infection in the investigated population was 5.78%. Higher percentage of HCV prevalence was detected in males than females in the age group 31-40 and 41-50. To compare the prevalence of HCV genotypes age-wise in male and female genotype 3a was found most prevalent genotype followed by 1a, 2a and 3b, respectively.

Abstract Let G be a graph with p vertices and q edges. A total neighborhood prime labeling of G is a labeling in which the vertices and edges are assigned labels from 1 to p + q such that the gcd of labeling in the neighborhood of each non degree 1 vertex is equal to 1 and the gcd of labeling in the edges of each non degree 1 vertex is equal to 1. A graph that admits a total neighborhood prime labeling is called a total neighborhood prime graph. In this paper, we examine total neighborhood prime labeling of trees such as (n, k, m) double star trees, spiders, caterpillars and firecrackers.

Abstract A new species, Actinimenes koyas sp. nov. (Decapoda: Palaemonidae) was collected at a depth of 1.0-2.0 m from the coral atoll of Agatti Island, Lakshadweep, Arabian Sea. The species was associated with the sea anemone, Heteractis magnifica (Quoy and Gaimard, 1833). It is the second representative of the genus Actinimenes Ďuriš and Horká, 2017 described from the Arabian Sea. Actinimenes koyas sp. nov. is closely related to A. ornatellus in terms of morphological traits. Actinimenes koyas sp. nov. is distinguished from Actinimenes ornatellus (Bruce, 1979) by the presence of a biramous outer antennular flagellum with three proximal segments fused, a shorter free ramus consisting of 7 to 8 segments with 12-14 groups of aesthetascs, a fourth thoracic sternite with V-shaped median incision and features of the telson and third maxilliped. The present new species is easily distinguished from the other three described species in the genus Actinimenes by the structural variation in the fourth sternal plate with a median notch. Additionally, a phylogenetic analysis inferred by Maximum Likelihood using the mitochondrial genes COI and 16S rRNA shows a close relationship of Actinimenes koyas sp. nov. with Actinimenes inornatus (Kemp, 1922). Pairwise genetic distances estimated using the COI and 16S data provided divergences between A. koyas sp. nov. and other congeneric species.

A tractor-operated automatic gun sprayer was developed for a cotton crop. The unit consists of frame structure, spray tank, horizontal triplex pump, control valves, spray gun nozzle, pressure gauge, strainer, hydraulic agitator and actuating mechanism. The power to drive the HTP pump was taken from the tractor power take off (PTO) through a belt and pulley. The actuating mechanism consists of motor and worm gear reduction. Two motors with 0.5 kW each (12 V dc) were used to provide oscillation motion to spray guns and motors get power from the tractor battery. The rotation angle of the spray gun is 30° horizontally. Provision was also made to fold the spray boom while in transport. The spray pattern could be adjusted based on the application of chemicals. This study was conducted to determine the suitable nozzle orientation (0°, 15° and 30° downwards) to field crops. The orientation of the spray nozzle was maintained by using the metal protractor. The laboratory experiments were carried out by using the actual cotton plant. The best nozzle orientation for maximum droplet density and droplet size as 15° downward. Leaf hopper [Amrasca biguttula (Ishida)] and aphids [Aphis gossypii (Glover)] control in the cotton crop after 7th day of spraying dinotefuran insecticide from the automatic gun sprayer and conventional tractor-operated gun sprayer was 87, 86 and 58 %, and 50 %, respectively. The total cost required to fabricate the sprayer was US$ 1008. The cost of operation of the tractor operated automatic gun sprayer was found to be US$ 4.7/ ha.

Resumo A infecção pelo vírus da hepatite B é perigosa entre os cinco tipos de hepatite, pois permanece clinicamente assintomática. O presente estudo traça a prevalência atualizada do vírus da hepatite B (HBV) na população geral de Mardan, Khyber Pakhtunkhwa, no Paquistão. Amostras de sangue de 4.803 indivíduos, incluindo 2.399 homens e 2.404 mulheres, foram investigadas. Todas as amostras suspeitas foram analisadas para o antígeno de superfície da hepatite B usando teste imunocromatográfico (ICT), enzyme-linked immunosorbent assay (ELISA), seguido por transcrição reversa-reação em cadeia da polimerase (RT-PCR). Os resultados mostraram que 312 (13,00%) de 2.399 indivíduos continham anticorpos no sangue contra o VHB, enquanto, entre as diferentes faixas etárias, as maiores incidências de anticorpos VHB foram encontradas nos grupos de 21 a 30 anos (10,73%). Além disso, amostras positivas para ICT foram rastreadas por reação em cadeia da polimerase aninhada para detectar a existência de HBV-DNA ativo. Observou-se que 169 (7,04%) de 2.399 homens do total da população (4803) testados foram positivos. Por outro lado, 463 mulheres (19,25%) possuíam anticorpos no sangue contra VHB. Acumulativamente, nossos resultados mostraram uma porcentagem maior de prevalência de HBV em homens do que em mulheres na faixa etária de 21 a 30 anos. O total de HCV infectados na população geral de Mardan foi registrado em 5,7%, incluindo homens e mulheres.

Abstract Hepatitis B virus infection is perilous among the five types of Hepatitis, as it remains clinically asymptomatic. The present study draws up-to-date prevalence of Hepatitis B virus (HBV) in the general population of Mardan, Khyber Pakhtunkhwa Pakistan. The blood samples from 4803 individuals including 2399 male and 2404 females were investigated. All the suspected samples were analyzed for hepatitis B surface antigen using Immuno-chromatographic test (ICT), Enzyme-linked immunosorbent assay (ELISA), and followed by Reverse transcription-polymerase chain reaction (RT-PCR). Results showed that 312 (13.00%) out of 2399 individuals contained antibodies in their blood against HBV, while among the different age groups, the highest incidences of HBV antibodies were found in the age of 21-30 groups (10.73%). Furthermore, the ICT positive samples were screened by nested polymerase chain reaction to detect the existence of active HBV-DNA. It was observed that 169 (7.04%) out of (2399) male of the total population (4803) tested was positive. On the other hand, the female 463 (19.25%) possessed antibodies in their blood against HBV. Accumulatively, our results showed a higher percentage of HBV prevalence in males than females in the age group 21-30 years. The total HCV infected in Mardan general population was recorded at 5.7% comprising both male and female.

ABSTRACT: This paper proposes a methodology to harvest the benefits of camber morphing airfoils for small unmanned aerial vehicle (SUAV) applications. Camber morphing using discrete elements was used to morph the base airfoil, which was split into two, three, and four elements, respectively, to achieve new configurations, into the target one. . In total, thirty morphed airfoil configurations were generated and tested for aerodynamic efficiency at the Reynolds numbers of 2.5 × 105 and 4.8 × 105, corresponding to loiter and cruise Reynolds numbers of a typical SUAV. The target airfoil performance could be closely achieved by combinations of 5 to 8 morphed configurations, the best of which were selected from a pool of thirty morphed airfoil configurations for the typical design specifications of SUAV. Interestingly, some morphed airfoil configurations show a reduction in drag coefficient of 1.21 to 15.17% compared to the target airfoil over a range of flight altitudes for cruise and loiter phases. Inspired by the drag reductions observed, a case study is presented for resizing a SUAV accounting for the mass addition due to the morphing system retaining the benefits of drag reduction.

Chemically modified styrene butadiene rubber (SBR) with nitro and chloro functionalities are prepared by the nitromercuration reaction of SBR through a phase transfer catalyst. Activation energy for this chemical reaction calculated from the time temperature data on the chemical reaction by the measurement of percentage of chlorine indicated that the reaction proceeded according to fist order kinetics. The chemical modification is characterized by FTIR, UV, NMR studies reveal the attachment functional group such as nitro and chloro group to the double bond of butadiene moiety. The glass transition temperature of the functionalized SBR is analyzed using differential scarming calorimetry. Thermogravimetric analysis (TGA) of the modified SBR is investigated in orderto study the basic decomposition pattern and thermal stability of the materials. Chemical modification of SBR is accompanied by a reduction of double bond which imparts excellent tensile strength. The fíame resistances of the modified samples are analyzed by the limiting oxygenindex value (LOI) and the result of the studies show that as the level modification increases the tendency of ealstomeric material to burn decreases.